Duramune Max 5/4L protects dogs against diseases caused by Canine Distemper, Adenovirus Type 1 (Hepatitis), Adenovirus Type 2 (respiratory disease), Parainfluenza and Parvovirus as well as four types of Leptospira (L. canicola, L. icterohaemorrhagiae, L. grippotyphosa, and L. pomona). Distemper, Adenovirus, Parainfluenza, and Parvovirus are modified live versions of the virus. Leptospira strains are killed bacterin. Recommended for the vaccination of healthy dogs six weeks of age or older. Contains twenty-five 1 ml doses.